Day 1 :
Keynote Forum
Metin Basaranoglu
Bezmialem Vakif University, Turkey
Keynote: Significant cohort of non-alcoholic fatty liver disease with portal vein thrombosis in transplant waiting list (Turkey)
Time : 10:00-11:00
Biography:
Metin Basaranoglu has completed his Master’s degree from Istanbul University. He has completed his Postdoctoral studies in St. Louis University School of Medicine/Liver Centre, USA. He has served on the Editorial Boards for the Journals and Referee for Gastroenterology, Hepatology and The American Journal of Gastroenterology. He is a Member of The American Association for the Study of Liver Diseases (AASLD) and The European Association for the Study of the Liver (EASL). He was awarded twice by AASLD and once by EASL.
Abstract:
The aim of the study is to characterize Non-Alcoholic Fatty Liver Disease (NAFLD) presentation with esophageal varices. We carried out a retrospective cohort study on 258 patients with esophageal varices at a single tertiary referral center. These patients underwent diagnosis of several liver diseases, including, NAFLD associated cirrhosis, hepatitis B, hepatitis C, Wilson disease, autoimmune liver diseases, and others. Of the 258 patients, 39% of patients exhibited esophageal varices due to NAFLD-associated cirrhosis. Of the 38 (14.7%) patients developed hepatocellular carcinoma during follow-up, 52% were due to hepatitis B, 26% due to hepatitis C and 13.2% due to NAFLD. Of the 258 patients, 50.0% with NAFLD, 33.3% with hepatitis B, 26.3% with hepatitis C and 58.3% with other diseases were alive at the end of the 5-year period with a significant difference according to the Kaplan-Meier log Rank test P=0.040). Portal vein thrombosis was detected in 47.5% of patients with NAFLD, in 29% of patients with hepatitis B, in 17% of patients with hepatitis C and in 62% of patients with other related diseases ( P<0.0001). Our study showed a proportionally greater elevation in liver transplant candidacy in patients with NAFLD and portal vein thrombosis. Older patients were more prone to developing cirrhosis, hepatocellular carcinoma, and a high mortality rate. However, younger patients exhibited more portal vein thrombosis and gastric varices.
Keynote Forum
Amin Gohary
Burjeel Hospital, UAE
Keynote: Vomiting of surgical significance
Time : 11:20-12:20
Biography:
Prof. Dr. Amin El-Gohary completed his MBBCh in 1972 and his Diploma in General Surgery in 1975 at Cairo University, Egypt. He was appointed as Chief Disaster Officer during Gulf War. He also held post as the Clinical Dean of Gulf Medical College, Ajman for 3 years. Prof. Dr. Amin is well known in Abu Dhabi for his extensive interest and involvement in scientific activities. He is the President of the Pediatric Surgical Association of UAE. He was awarded the Shield of the College of Pakistan and the Medal of International Recognition in pediatric urology from the Russian Association of Andrology. Prof. Dr. Amin is also the founder and member of the Arab Association of Pediatric Surgeons. Prof. Dr. Amin has an intensive academic and teaching experience, has written several publications in distinguished medical journals, and has made several poster and paper presentations in national and international conferences. Currently, he is an external examiner for the Royal College of Surgeons.
Abstract:
Vomiting in children is common and mostly related to the medical condition. However, there are surgical conditions associated with vomiting which needs to be acknowledged and diagnosed early. Bilious vomiting is an ominous symptom and needs to be taken seriously. Any baby who vomits bile should be considered as having an underlying intestinal obstruction until proved otherwise.
- Liver Disease and Pregnancy | Pediatric and Geriatric Hepatology | Hepato-Biliary Diseases | Liver Transplantation and Surgery | Liver Imaging Modalities | Hepatitis | Hepatic Pathology | Liver Cancer
Location: Hall
Chair
Metin Basaranoglu
Bezmialem Vakif University
Biography:
Yasser Rashed is working as an Associate Professor of Pediatric Hepatology and Gastroenterology. He has published many articles in the field of pediatric hepatology and gastroenterology. He has completed Medical Doctorate in Pediatric Hepatology and Master’s in Pediatric Hepatology and also in Pediatrics.
Abstract:
Autoimmune Hepatitis (AIH) is a progressive necroinflammatory liver disease associated with significant morbidity and mortality. Mainly affecting females, AIH has a varied clinical presentation from minor symptomatology to acute liver failure. Mutation of complement factor 4 found in patient with AIH. Selective Ig A deficiency found in patient with AIH. Multiple lines of evidence suggest that hepatic viral infections may trigger autoimmune reactions, including AIH in immunologically susceptible hosts. Molecular mimicry between the proteins of both HBV and HCV and human nuclear and smooth muscle auto antigens has been identified and may explain production of autoantibodies in these viral infections. In Europe, approximately 10% of pediatric HCV infections are associated with anti-LKM1 autoantibodies. As noted earlier, susceptibility for AIH in the is associated with the HLA class II allele DRB1*1301 that has been associated with protracted HAV infection and development of AIH. Thus, it is possible that the DRB1*1301 allele may confer susceptibility for AIH by encoding class II. How to diagnose AIH, How to treat, When you stop treatment?